Generics
Pregabalin
Used For
Neuropathic Pain
How it works
Pregabalin reduces neuronal calcium currents by binding to the alpha-2-delta subunit of voltage gated calcium channels in CNS tissues and this particular mechanism may be responsible for effects in neuropathic pain, anxiety and other pain syndromes.
Side Effects
Very common: Dizziness, drowsiness and somnolence. Common:Increased appetite, euphoric mood, confusion, irritability, decreased libido, disorientation, insomnia, ataxia, abnormal coordination, tremor, dysarthria, memory impairment, disturbance in attention, paraesthesia, sedation, balance disorder, lethargy, headache, blurred vision, diplopia, vertigo, vomiting, dry mouth, constipation, flatulence, erectile dysfunction,
Drug Interactions
CNS depressants such as opiates or benzodiazepines , ethanol , lorazepam , oxycodone.
Indication
Pregabalin is indicated: – For the management of neuropathic pain associated with diabetic peripheral neuropathy. – For the management of postherpetic neuralgia. – For the treatment of pain associated with spinal cord injury . – As adjunctive therapy in adults with partial seizures with or without secondary generalization.- For the treatment of Generalized Anxiety Disorder (GAD) in adults. – For the treatment of fibromyalgia syndrome (FMS).



