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SOLU CORTEF 100MG INJ

SOLU CORTEF 100MG INJ

₨ 2,402 / per unit

SOLU CORTEF 100MG INJ

₨ 2,402 / per unit

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Requires Prescription (YES/NO)

Yes

Generics

Hydrocortisone sodium succinate

Used For

Pain & Inflammation

How it works

Hydrocortisone sodium succinate has the same metabolic and anti-inflammatory actions as hydrocortisone. When given parenterally and in equimolar quantities, the two compounds are equivalent in biologic activity. The highly water-soluble sodium succinate ester of hydrocortisone permits the immediate intravenous administration of high doses of hydrocortisone in a small volume of diluent and is particularly useful where high blood levels of hydrocortisone are required rapidly. Following the intravenous injection of hydrocortisone sodium succinate, demonstrable effects are evident within one hour and persist for a variable period.

Usage And Safety

Dosage

Dose should be based on severity of disease and patient response. Adults : Anyi-inflammatory or immunosuppressive : Oral/IM/IV : 15-240mg every 12hr. Adrenal insufficiency : Oral : 100mg IV bolus , then 300mg/day in divided doses every 8hr or as a continuous infusion for 48hr; once patient is stable change to oral, 50mg every 8hr for 6 doses, then taper to 30-50mg/day in divided doses. Children : Inflammatory bowel disease , induction of remission : IV injection : 2-18yr, 2.5mg/kg (max 100mg) every 6hr. IV infusion : 2-18yr , 10mg/kg daily (max 400mg daily ). Acute hypersensitivity reactions, angioedema : IM or IV injection . Under 6mnth, initially 25mg 3 times daily, adjusted according to response ; 6mnth-6yr, initially 50mg 3 times daily, adjusted according to response ; 6-12yr, initially 100mg 3 times daily, adjusted according to response; 12-18yr, initially 200mg 3 times daily, adjusted according to response. OR As directed by your physician.

Side Effects

• Allergic reactions, such as skin rash, swelling of the face or wheezing and difficulty breathing. This type of side effect is rare, but can be serious. • Acute pancreatitis, stomach pain which may spread through to your back, possibly accompanied by vomiting, shock and loss of consciousness. • Ulcers or bleeding ulcers, symptoms of which are severe stomach pain which may go through to the back and could be associated with bleeding from the back passage, black or bloodstained stools and/or vomiting blood • Pulmonary embolus (blood clot in the lung) symptoms include sudden sharp chest pain, breathlessness and coughing up blood.• Raised pressure within the skull of children (pseudotumour cerebri) symptoms of which are headaches with vomiting, lack of energy and drowsiness. This side effect usually occurs after treatment is stopped.• Thrombophlebitis (blood clots or thrombosis in a leg vein), symptoms of which include painful swollen, red and tender veins.

Drug Interactions

Acetazolamide , Aminoglutethimide , Anticoagulants , Anticholinergics , Anticholinesterases , Antibiotics , Antidiabetics , Antiemetic , Aspirin , Barbiturates, carbamazepine, phenytoin and primidone , Carbenoxolone and cimetidine , Ciclosporin , Digoxin , Diltiazem or mibefradil , Diuretics , Isoniazid , Antivirals (such as ritonavir, indinavir) , Ethinylestradiol / Norethindrone , Ketoconazole or itraconazole , Pancuronium , Rifampicin and rifabutin , Tacrolimus and cyclophosphamide , Vaccines , Grapefruit juice

Indication

It is used to treat shock following surgery, injuries, hypersensitivity (anaphylactic) reactions or other stressful conditions.

When not to Use

Do not use : • If you think you have ever suffered an allergic reaction, or any other type of reaction after being given Hydrocortisone sodium succinate, or any other medicine containing a corticosteroid, or any of the other ingredients of this medicine . An allergic reaction may cause a skin rash or reddening, swollen face or lips or shortness of breath. • If you have any fungal infection (such as thrush) which is not being treated. • If you have recently had, or are about to have any vaccination.

Precautions

Precaution

Caution should be exercised with corticosteroids as they can cause an eye condition (central serous chorioretinopathy) where a collection of fluid forms under the light-sensitive layer of tissue at the back of the inner eye (retina) causing visual impairment and may lead to retinal detachment.

Warnings

Warning 1

If hydrocortisone is given to a prematurely born baby, monitoring of heart function and structure may be needed.

Warning 2

Tell your doctor if you suspect an infection has occurred, as corticosteroids can make infections more likely and may mask their signs.

Warning 3

Long term therapy of corticosteroids in high doses can cause an abnormal amount of fat deposition on or outside the lining of the spine (epidural lipomatosis).

Additional Information

Pregnancy category

Always consult your physician before using any medicine.

Storage (YES/NO)

Store this medicine at room temperature, away from direct light and heat.

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