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Levosulpiride’s primary mechanism of action is as a selective antagonist of dopamine D2 and D3 receptors, primarily in the gastrointestinal tract and central nervous system. It preferentially binds to presynaptic autoreceptors, leading to a decrease in dopamine release. In the gastrointestinal tract, this action reduces dopamine-mediated inhibition of gastric motility and increases gastric, biliary, and pancreatic secretions, enhancing gastrointestinal motility and digestive processes. In the central nervous system, levosulpiride’s action on dopamine receptors may contribute to its effects on nausea and vomiting by influencing the chemoreceptor trigger zone. Additionally, it may have indirect effects on other neurotransmitter systems, such as serotonin and acetylcholine, which could further contribute to its therapeutic actions.
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Ingredients
Levosulpiride 50mg
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Uses
The following are the uses of Levosulpiride 50mg Tablet:
- Used for treating digestive problems like dyspepsia, gastroesophageal reflux disease (GERD), and functional indigestion.
- Used to manage symptoms of nausea and vomiting, especially in post-operative or chemotherapy patients.
- Used for effective relief from heartburn and upper abdominal pain.
- Used to stimulate gastric motility and improve digestion.
- Used in the treatment of functional gastrointestinal disorders, such as irritable bowel syndrome (IBS).
- Used to reduce symptoms of bloating, fullness, and early satiety.
- Used for short-term management of anxiety-related gastrointestinal symptoms.




