Generics
Nitroglycerine
Used For
Angina
Side Effects
Adverse effects include facial flushing and headache. Toxic effects of Nitroglycerine include vomiting, restlessness, cyanosis, methaemoglobinaemia and syncope. They disappear on dosage reduction and usually do not necessitate the discontinuation of the treatment. Regular use of Nitroglycerine (3 times a day) should be avoided because of the development of tolerance. 2 times daily administration and withdrawal for a short period may reestablish the original sensitivity.
Drug Interactions
Nitroglycerine may enhance the effects of peripheral vasodilators. The hypotensive effects of nitrates are potentiated by concurrent administration of sildenafil.
Indication
It is indicated for : The prophylaxis of angina pectoris. Prevention and treatment of effort and vasospastic angina. Supplementary treatment of heart failure refractory to digitalis and diuretic treatment.




