METXONE TAB 5MG 10`S
₨ 60 / per unit
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Generics
Metolazone
Used For
Hypertension
Side Effects
Cardiovascular: Chest pain/discomfort, orthostatic hypotension, excessive volume depletion, hemoconcentration, venous thrombosis, palpitations. Central and Peripheral Nervous System: Syncope, neuropathy, vertigo, paresthesias, psychotic depression, impotence, dizziness/lightheadedness, drowsiness, fatigue, weakness, restlessness, sometimes resulting in insomnia), headache. Dermatologic/Hypersensitivity: Necrotizing angitis (cutaneous vasculitis), Stevens-Johnson Syndrome (SJS), Toxic Epidermal Necrolysis (TEN), purpura, dermatitis (photosensitivity), urticaria and skin rashes. Gastrointestinal: Hepatitis: intrahepatic cholestatic jaundice, pancreatitis, vomiting, nausea, epigastric distress, diarrhea, constipation, anorexia, abdominal bloating. Hematologic: Aplastic/hypolastic anemia, agranulocytosis, leukopenia
Drug Interactions
Alcohol, barbiturates, or narcotics , Antihypertensives , Corticosteroids or ACTH Therapy , curariform drugs (such as tubocurarine) , Digitalis , Drugs Used to Treat Gout , Furosemide and Other Loop Diuretics , Insulin and Oral Antidiabetic Agents , Lithium , Methenamine , Salicylates and Other Nonsteroidal Anti-inflammatory Agents , Sympathomimetics.
Indication
Metolazone is indicated for the treatment of edema accompanying congestive heart failure and edema accompanying renal diseases including the nephrotic syndrome and states of diminished renal function. Metolazone has also been used in the management of mild to moderate essential hypertension alone or in combination with other antihypertensive drugs of a different class.
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