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Generics

Metoprolol Tartrate

Used For

Hypertension

How it works

Metoprolol belongs to a class of drugs known as beta blockers. It works by blocking the action of certain natural chemicals in your body, such as epinephrine, on the heart and blood vessels. This effect lowers the heart rate, blood pressure, and strain on the heart.

Usage And Safety

Dosage

• High blood pressure: : Initially 100mg metoprolol tartrate daily. The dose may be increased to 400mg daily in single or divided doses.• Angina: 50-100mg metoprolol tartrate two or three times daily.• Irregular heart beats (arrhythmia): 50mg metoprolol tartrate two or three times daily. The dose may be increased to 300mg daily in divided doses.• Heart attacks: 50mg metoprolol tartrate every six hours. The usual maintenance dose is 200mg daily in divided doses. The medicine should be taken for at least 3 months. • Prevention of migraine: 100-200mg metoprolol tartrate daily in divided doses (in the morning and evening). Children : Not Recommended. Always consult to your doctor or pharamcist for dose adjustments.

Side Effects

Common (may affect up to 1 in 10 people): tiredness, dizziness, headache, a slow heart rate, feeling faint on standing due to low blood pressure, shortness of breath with or without strenuous physical activity, feeling or being sick, stomach pain. Rare (may affect up to 1 in 1,000 people): depression, nightmares, inability to think clearly, sleepiness or difficulty in sleeping, tingling or ‘pins and needles’, difficulty breathing, heart failure, irregular heart rate, palpitation, water retention causing swelling, Raynaud’s phenomenon.

Drug Interactions

Monoamine oxidase inhibitors (MAOIs) , verapamil, nifedipine and diltiazem , disopyramide or quinidine , cimetidine , hydralazine, clonidine or prazosin , amiodarone and propafenone , tricyclic or SSRI antidepressants , barbiturates , phenothiazines , anaesthetics such as cyclopropane or trichloroethylene , aldesleukin , alprostadil , anxiolytics or hypnotics , indometacin or celecoxib , rifampicin (antibiotic) or terbinafine , lidocaine , moxisylyte , tropisetron , diphenydramine.

Indication

It is used to treat : • High blood pressure • Angina pectoris (pain in the chest caused by blockages in the arteries to the heart) • Irregular heart rhythm (arrhythmia) • The symptoms caused by an overactive thyroid gland (thyrotoxicosis ) .

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