Generics
Cefixime
Used For
Bacterial Infection
How it works
Like other cephalosporins, cefixime exhibits its bactericidal action by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall, causing the inhibition of the third and last stage of bacterial cell wall synthesis.
Usage And Safety
Dosage
The recommended adult dose of (Cefixime) is 200 – 400mg daily according to the severity of infection, given either as a single dose or in two divided doses. Children : 6-12mg/kg/day in two divided doses.Lower Respiratory Infection : Adults & Children : >12 yr or >50 kg : 400 mg once daily or 200 mg every 12 hr. <50 kg or > 6 mnth : 8 mg/kg once daily or 4 mg/kg every 12 hr. Otitis Media : Adults : Adults & Children : >12 yr ot >50 kg : 400 mg once daily or 200 mg every 12 hr . <50 kg or 6 mnth : 8 mg/kg once daily or 4 mg/kg every 12 hr. Always consult your doctor or pharmacist for dose adjustments.
Side Effects
Diarrhea (if severe diarrhea occurs, cefixime should be discontinued), changes in the color of stool, nausea, abdominal pain, dyspepsia, vomiting, Headache, dizziness, seizures , Transient rises in liver transaminases,alkaline phosphatase and jaundice , elevation of serum amylase.
Drug Interactions
Anticoagulants , Carbamazepine , probenecid.
Indication
Cefixime is indicated in the treatment of the following infections when caused by susceptible strains of the designated microorganisms: – Uncomplicated urinary tract infections – Otitis media – Pharyngitis and tonsillitis – Acute bronchitis and acute exacerbations of chronic bronchitis – Uncomplicated gonorrhea (cervical/urethral




