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Prednisolone is a corticosteroid medication used to reduce inflammation and suppress the immune system. It works by mimicking the effects of cortisol, a hormone produced by the adrenal glands. Prednisolone binds to glucocorticoid receptors inside cells, which then enter the nucleus and influence gene expression. This results in a decrease in the production of inflammatory substances like prostaglandins and leukotrienes. Additionally, prednisolone helps regulate immune responses by reducing the activity of immune cells, thus alleviating symptoms of various inflammatory and autoimmune conditions. It is commonly used to treat conditions such as asthma, allergies, and rheumatoid arthritis.
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Ingredients
Prednisolone -
Drug Class
Corticosteroid
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Dosage Form
Tablet -
Uses
This medication is used to treat:
- Inflammation
- Allergic Reactions
- Autoimmune Disorders
- Corticosteroid Replacement
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Dosage
Prednisolone dosage recommendations are:
- Nephrotic syndrome – Child – Standard regimen – 60 mg/m² daily in 3 divided doses for 4 weeks, followed by 40 mg/m² on alternate days for 4 weeks.
- Acute exacerbations in multiple sclerosis – Adult – 200 mg daily for 1 week, followed by 80 mg every other day for 1 month.
- Anti-inflammatory or immunosuppressive – Adult – Initial range – 5-60 mg daily, may be divided daily doses or a single morning dose, or alternate days. Use the lowest effective dose for the shortest period. Child – 0.14-2 mg/kg daily in 3 or 4 divided doses. Use the lowest effective dose for the shortest duration.
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In case of Overdose
Too many tablets can make you unwell. Contact your doctor or nearest hospital accident and emergency department.
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Missed Dose
If you miss a dose, take it as soon as you remember. If it is close to the next dose, skip the missed dose. Do not double up.
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How To Use
The tablets should only be taken by mouth and can be swallowed with water. They can be taken before or after a meal.
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When Not to Use
Do not take Prednisolone Enteric coated if you:
- Are suffering from an untreated widespread (systemic) infection
- Are allergic to prednisolone or any of the other ingredients
- Are suffering from a herpes infection of the eye
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Side Effects
The side effects of Prednisolone tablets are as follows:
- Gastrointestinal discomfort
- Weight gain
- Mood changes
- Increased appetite
- Insomnia





